3017891
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Early and Established Rheumatoid Arthritis (RA) Panel

RAPANEL

Ordering Recommendation

Use to identify rheumatoid arthritis (RA). This panel may have enhanced sensitivity due to the inclusion of 14-3-3 eta protein alongside conventional rheumatoid factor (RF) and anticyclic citrullinated peptide (anti-CCP) antibody. 14-3-3 eta is also used to stratify disease activity and monitor treatment effectiveness. 

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Fasting specimen preferred.

Collect

Serum separator tube (SST) or red top.

Specimen Preparation

Allow serum to clot completely at room temperature before centrifuging. Transfer 2 mL serum to an ARUP standard transport tube. (Min: 1 mL) Serum is the only acceptable specimen type for this assay without a disclaimer.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Nonserum, contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month (should not be thawed more than once)

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)/Quantitative Immunoturbidimetry/Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)

Performed

Sun-Sat

Reported

1-8 days

Reference Interval

Test Number
 Components
 Reference Interval
  14-3-3 eta Protein, Serum 0.19 ng/mL or less
  Cyclic Citrullinated Peptide Ab, IgG/A 19 Units or less
  Rheumatoid Factor 0-14 IU/mL

Interpretive Data

Refer to report.

Compliance Category

Analyte Specific Reagent (ASR)

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
10/21/2024
X
N/A

CPT Codes

83520; 86200; 86431

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Components

Component Test Code* Component Chart Name LOINC
0050465 Rheumatoid Factor 11572-5
3016633 Cyclic Citrullinated Peptide Ab, IgG/A 57093-7
3017892 14-3-3 eta Protein, Serum 75880-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • 14-3-3 eta
  • 14.3.3 eta
  • CCP and RF
  • RA Panel
  • RF and CCP IgG
  • Rheumatoid Arthritis Profile
Early and Established Rheumatoid Arthritis (RA) Panel